SUV39H1 monoclonal antibody, clone 42AT239.96.72
产品名称： SUV39H1 monoclonal antibody, clone 42AT239.96.72
英文名称： SUV39H1 monoclonal antibody, clone 42AT239.96.72
产品编号： MAB1156
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant SUV39H1.
- Immunogen:
- Recombinant GST fusion protein corresponding to N-terminus of human SUV39H1.
- Host:
- Mouse
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.
Ostrup O, Hyttel P, Klarke DA, Collas P.Biochem Biophys Res Commun. 2011 Sep 2;412(3):487-93. Epub 2011 Aug 6.
- 2.
- MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output.
Chen L, Li Z, Zwolinska AK, Smith MA, Cross B, Koomen J, Yuan ZM, Jenuwein T, Marine JC, Wright KL, Chen J.EMBO J. 2010 Aug 4;29(15):2538-52. Epub 2010 Jun 29.
- 3.
- EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization.
Goyama S, Nitta E, Yoshino T, Kako S, Watanabe-Okochi N, Shimabe M, Imai Y, Takahashi K, Kurokawa M.Leukemia. 2010 Jan;24(1):81-8. Epub 2009 Sep 24.
- 4.
- p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1.
Cherrier T, Suzanne S, Redel L, Calao M, Marban C, Samah B, Mukerjee R, Schwartz C, Gras G, Sawaya BE, Zeichner SL, Aunis D, Van Lint C, Rohr O.Oncogene. 2009 Sep 24;28(38):3380-9. Epub 2009 Jul 6.
- Entrez GeneID:
- 6839
- Protein Accession#:
- XM_047059
- Gene Name:
- SUV39H1
- Gene Alias:
- KMT1A,MG44,SUV39H
- Gene Description:
- suppressor of variegation 3-9 homolog 1 (Drosophila)
- Omim ID:
- 300254
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq
- Other Designations:
- H3-K9-HMTase 1,OTTHUMP00000024298,Su(var)3-9 homolog 1,histone H3-K9 methyltransferase 1,histone-lysine N-methyltransferase, H3 lysine-9 specific 1,suppressor of variegation 3-9 homolog 1
- Gene Pathway