PTCH1 polyclonal antibody
产品名称： PTCH1 polyclonal antibody
英文名称： PTCH1 polyclonal antibody
产品编号： PAB12543
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTCH1.
- Immunogen:
- A synthetic peptide corresponding to amino acids 269-279 of human and mouse PTCH1/Ptch1.
- Host:
- Rabbit
- Reactivity:
- Chicken, Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:500-1:1000)
Immunocytochemistry (1:500-1:1000)
Immunohistochemistry (Frozen sections) (1:500-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro.
Smith S, Stillman B.J Biol Chem. 1991 Jun 25;266(18):12041-7.
- Entrez GeneID:
- 5727
- Gene Name:
- PTCH1
- Gene Alias:
- BCNS,FLJ26746,FLJ42602,HPE7,NBCCS,PTC,PTC1,PTCH,PTCH11
- Gene Description:
- patched homolog 1 (Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq
- Other Designations:
- OTTHUMP00000021709,OTTHUMP00000021710,PTCH protein +12b,PTCH protein +4',PTCH protein -10,patched