ITGAM monoclonal antibody, clone MEM-174 (PE)-抗体-抗体-生物在线
亚诺法生技股份有限公司(Abnova)
ITGAM monoclonal antibody, clone MEM-174 (PE)

ITGAM monoclonal antibody, clone MEM-174 (PE)

商家询价

产品名称: ITGAM monoclonal antibody, clone MEM-174 (PE)

英文名称: ITGAM monoclonal antibody, clone MEM-174 (PE)

产品编号: MAB4552

产品价格: null

产品产地: 台湾

品牌商标: Abnova

更新时间: null

使用范围:

亚诺法生技股份有限公司(Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
  • 传真 : 点击查看
  • 邮箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGAM.
  • Immunogen:
  • Native purified ITGAM from human granulocytes.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 165-170
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes CD11b antigen (Mac-1 alpha), a 165-170 KDa type I transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Isotype:
  • IgG2a
  • Storage Buffer:
  • In PBS (0.2% BSA, 15 mM sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3684
  • Gene Name:
  • ITGAM
  • Gene Alias:
  • CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
  • Gene Description:
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit

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