Anti-Caspase-9 Monoclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K000130M-50ul	Solarbio	50ul	960.00元
K000130M-100ul	Solarbio	100ul	1600.00元

英文名称	Mouse Caspase-9 Monoclonal Antibody
应用2	WB
克隆类型2	Monoclonal Antibody
别名	Caspase-9
应用	WB
稀释比例	WB1:1000 ICC
交叉反应	Human
蛋白分子量	49,37kDa
Gene ID	842
保存	Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 69% Glycerol.
纯化方法	Affinity purification
亚型	IgG1
免疫原	Purified recombinant human Caspase-9 protein fragments expressed in E.coli.
性状	Lyophilized or Liquid
Swiss Prot	P55211
克隆号	1D1-F2-E9
克隆类型	Monoclonal Antibody
来源	Mouse
背景资料	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.