CAMK1 (C-term) Peptide
产品名称： CAMK1 (C-term) Peptide
英文名称： CAMK1 (C-term) Peptide
产品编号： P2374
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CAMK1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CAMK1.
- Host:
- Rabbit
- Reactivity:
- Human, Monkey, Mouse, Rat
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase.
Condon JC, Pezzi V, Drummond BM, Yin S, Rainey WE.Endocrinology. 2002 Sep;143(9):3651-7.
- 2.
- Characterization of substrate phosphorylation and use of calmodulin mutants to address implications from the enzyme crystal structure of calmodulin-dependent protein kinase I.
Chin D, Winkler KE, Means AR.J Biol Chem. 1997 Dec 12;272(50):31235-40.
- 3.
- Human calcium-calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine-177 by calcium-calmodulin dependent protein kinase I kinase.
Haribabu B, Hook SS, Selbert MA, Goldstein EG, Tomhave ED, Edelman AM, Snyderman R, Means AR.EMBO J. 1995 Aug 1;14(15):3679-86.
- Applications
- Western Blot (Transfected lysate)
- Western blot analysis of CAMK1 (arrow) using CAMK1 polyclonal antibody (Cat # PAB2769). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CAMK1 gene (Lane 2) (Origene Technologies).
- Western Blot
- The CAMK1 polyclonal antibody (Cat # PAB2769) is used in Western blot to detect CAMK1 in HeLa cell lysate (lane 1) and primate brain tissue lysate (lane 2) .
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with CAMK1 polyclonal antibody (Cat # PAB2769) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 8536
- Protein Accession#:
- Q14012
- Gene Name:
- CAMK1
- Gene Alias:
- CAMKI,MGC120317,MGC120318
- Gene Description:
- calcium/calmodulin-dependent protein kinase I
- Omim ID:
- 604998
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq
- Other Designations:
- OTTHUMP00000158527